Specifically Regional Cerebral Hypoperfusion in a Case of Highly Suspected Sporadic Creutzfeldt-Jakob Disease on 99mTc-ECD SPECT/CT with Easy Z-Score Imaging System Analysis

Autor:	Shun-Chieh Chen, Daniel Hueng-Yuan Shen, Hung-Yen Chan, Ming-Hui Yang, Hung-Pin Chan
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	99mTc-ECD brain SPECT cerebral hypoperfusion Creutzfeldt-Jakob Disease MRI SPECT/CT Medicine (General) R5-920
Zdroj:	Diagnostics, Vol 12, Iss 2, p 437 (2022)
Druh dokumentu:	article
ISSN:	2075-4418
DOI:	10.3390/diagnostics12020437
Popis:	Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly-progressive dementing illness, the challenge of diagnosis during life. We presented a 78-year-old woman reported stupor, right facial palsy, and fluctuations in consciousness. 99mTc-ECD brain SPECT/CT with eZIS analysis revealed significant decreased regional cerebral blood flow mainly in specific regions of Alzheimer’s disease as the published article reported with involving frontal region. Brain DWI MRI increased signal intensities corresponding to similar location of 99mTc-ECD brain SPECT/CT. In this case, we reported the pattern of decreased rCBF may correlate to rapidly progressive dementia and associated neurodegenerative symptoms of the highly suspected sCJD patient.
Databáze:	Directory of Open Access Journals
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