Zinc levels and features of atopic dermatitis in children
| Autor: | T.V. Sorokman, N.O. Popely |
|---|---|
| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Zdorovʹe Rebenka, Vol 15, Iss 2, Pp 86-91 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2224-0551 2307-1168 |
| DOI: | 10.22141/2224-0551.15.2.2020.200270 |
| Popis: | Background. Searching for the fundamental pathogenic mechanisms of atopic dermatitis (AD) and improvement of options for prevention and treatment, increasing attention is paid to the state of trace elements supply of the child’s body. Particular role is given to zinc, which is one of the most versatile trace elements. The purpose was to study the features of atopic dermatitis in children depending on the serum content of zinc. Materials and methods. The paper presents the materials of clinical observation, clinical laboratory and instrumental examination of 168 children aged 7 to 18 years with AD. The control group consisted of 60 healthy children. The serum zinc content was determined by atomic absorption spectroscopy on a C-115-M1 spectrophotometer according to the instructions that are attached to the device. Results. More than half of children (55.6 %) had very low levels of zinc (0.35 ± 0.11 mg/l), while another 22.2 % had extremely low levels (0.12 ± 0.02 mg/l). Several features of AD clinical course were noted: more frequent episodes of acute respiratory infection, predominance of moderate and severe course with periorbital, perioral, perianal dermatitis, dystrophic changes and hyperkeratosis of the nails, increased hair brittleness, expressed skin dryness (2.31 ± 0.73 vs. 1.92 ± 0.69 points, p |
| Databáze: | Directory of Open Access Journals |
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