STUDYING OF APPLICATION IMMUNOMODULATOR «GALAVIT» AT EXPERIMENTAL ATHEROSCLEROSIS

Autor: E. P. Turmova, A. A. Grigoryuk, E. A. Bichkov, E. V. Markelova, I. V. Chihkalovets
Jazyk: ruština
Rok vydání: 2012
Předmět:
Zdroj: Acta Biomedica Scientifica, Vol 0, Iss 3(2), Pp 323-326 (2012)
Druh dokumentu: article
ISSN: 2541-9420
2587-9596
Popis: The changes of the cytokines and lipidic spectrum at experimental hyperlipoidemia and arterial hypertensia was made at 20 rats «Vistar» during 6 months. As the material of research was the blood serum. The cytokines was made by the method solid-phase not competitive immune-enzyme analysis with the use of sets: Rat «R&D Diagnostics Inc.», USA. The content of the general cholesterol; triglycerides; LDL; HDL was investigated by the method of standard colorimetric analysis with the use of reagents «Olveks diagnosticum» (Russia). The increasing of the general cholesterol, LDL; HDL, atherogenic coefficient, IFN-γ and IL-1β in blood of animals was revealed. At application of immunomodulator «Galavit» at experimental atherosclerosis the decreasing contains of IL-1, IFN-γ, the level of general cholesterol; LDL; HDL, atherogenic coefficient is fixed.
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