Autor: |
Young Geun Mok, Ji Min Lee, Eugene Chung, Jaesuk Lee, Kayeong Lim, Sung-Ik Cho, Jin-Soo Kim |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-022-31745-y |
Popis: |
Monomeric DdCBEs (mDdCBEs), enabling mitochondrial DNA editing with high efficiencies of up to 50%, when transiently expressed in cultured human cells and nearly homoplasmic C-to-T editing via AAV. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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