A case of intracranial hemorrhage in a neonate with congenital factor VII deficiency
| Autor: | Won Seok Lee, Young Sil Park |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Korean Journal of Pediatrics, Vol 53, Iss 10, Pp 913-916 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1738-1061 2092-7258 |
| DOI: | 10.3345/kjp.2010.53.10.913 |
| Popis: | Congenital factor VII deficiency is a rare autosomal-recessive bleeding disorder. Bleeding manifestations and clinical findings vary widely, ranging from asymptomatic subjects to patients with hemorrhages that may cause significant handicaps. Treatment has traditionally involved factor VII(FVII) replacement therapy using fresh frozen plasma, prothrombin complex concentrates or plasma-derived FVII concentrates. Recombinant activated FVII (NovoSeven®) is currently considered the first-line treatment for replacement therapy of FVII deficiency. Here we present a case of severe intracerebral and intraventricular hemorrhage in a neonate with congenital FVII deficiency. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|