Biofilm production by multiresistant Corynebacterium striatumassociated with nosocomial outbreak
| Autor: | Cassius de Souza, Yuri Vieira Faria, Lincoln de Oliveira Sant’Anna, Vanilda Gonçalves Viana, Sérgio Henrique Seabra, Mônica Cristina de Souza, Verônica Viana Vieira, Raphael Hirata Júnior, Lílian de Oliveira Moreira, Ana Luíza de Mattos-Guaraldi |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Memorias do Instituto Oswaldo Cruz, Vol 110, Iss 2, Pp 242-248 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1678-8060 0074-0276 |
| DOI: | 10.1590/0074-02760140373 |
| Popis: | Corynebacterium striatum is a potentially pathogenic microorganism that causes nosocomial outbreaks. However, little is known about its virulence factors that may contribute to healthcare-associated infections (HAIs). We investigated the biofilm production on abiotic surfaces of multidrug-resistant (MDR) and multidrug-susceptible (MDS) strains of C. striatum of pulsed-field gel electrophoresis types I-MDR, II-MDR, III-MDS and IV-MDS isolated during a nosocomial outbreak in Rio de Janeiro, Brazil. The results showed that C. striatum was able to adhere to hydrophilic and hydrophobic abiotic surfaces. The C. striatum1987/I-MDR strain, predominantly isolated from patients undergoing endotracheal intubation procedures, showed the greatest ability to adhere to all surfaces. C. striatumbound fibrinogen to its surface, which contributed to biofilm formation. Scanning electron microscopy showed the production of mature biofilms on polyurethane catheters by all pulsotypes. In conclusion, biofilm production may contribute to the establishment of HAIs caused by C. striatum. |
| Databáze: | Directory of Open Access Journals |
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