Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population

Autor: Chia-Hsin Wu, Chia-Shan Hsieh, Yo-Cheng Chang, Chi-Cheng Huang, Hsien-Tang Yeh, Ming-Feng Hou, Yuan-Chiang Chung, Shih-Hsin Tu, King-Jen Chang, Amrita Chattopadhyay, Liang-Chuan Lai, Tzu-Pin Lu, Yung-Hua Li, Mong-Hsun Tsai, Eric Y. Chuang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-021-02597-x
Popis: Wu, Hsieh et al. analyze Taiwanese breast cancer patient samples using whole-exome sequencing to examine the heterogeneity and homogeneity in the timing and dependencies of somatic aberrations across disease subtypes. The authors focus on somatic alterations and related features that correlate with whole genome doubling, including homologous recombination deficiencies.
Databáze: Directory of Open Access Journals
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