| Autor: |
Yating Zhang, Dunhua Zhou, Han Xia, Jian Wang, Huaqing Yang, Luhong Xu, Ke Huang, Jianpei Fang |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Molecular and Cellular Probes, Vol 67, Iss , Pp 101889- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
0890-8508 |
| DOI: |
10.1016/j.mcp.2022.101889 |
| Popis: |
Objective: Infection is one of the most common causes of death in children with hematological diseases. Here, we aim to investigate the value of metagenomic next-generation sequencing (mNGS) in the detection of causative pathogens in children with hematological diseases. Methods: In this retrospective study, specimens from children with hematological diseases, who were admitted to Sun Yat-Sen University between June 2019 and September 2021, were collected for culture and mNGS. Results: A total of 67 pediatric patients were enrolled, and 96 specimens were collected. The positive rate of mNGS was significantly higher than that of culture (57.2% vs 12.5%, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect