Involvement of the Expression of G Protein-Coupled Receptors in Schizophrenia

Autor:	Raluka Kalinovic, Andrei Pascariu, Gabriela Vlad, Diana Nitusca, Andreea Sălcudean, Ioan Ovidiu Sirbu, Catalin Marian, Virgil Radu Enatescu
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	schizophrenia G protein-coupled receptors psychosis cognitive deficit super conserved receptor expressed in the brain Medicine Pharmacy and materia medica RS1-441
Zdroj:	Pharmaceuticals, Vol 17, Iss 1, p 85 (2024)
Druh dokumentu:	article
ISSN:	1424-8247
DOI:	10.3390/ph17010085
Popis:	The expression of GPCRs has been associated with schizophrenia, and their expression may induce morphological changes in brain regions responsible for schizophrenia and disease-specific behavioral changes. The articles included in this review were selected using keywords and databases of scientific research websites. The expressions of GPRs have different involvements in schizophrenia, some increase the risk while others provide protection, and they may also be potential targets for new treatments. Proper evaluation of these factors is essential to have a better therapeutic response with a lower rate of chronicity and thus improve the long-term prognosis.
Databáze:	Directory of Open Access Journals
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