Cell-mediated and humoral immunity in west syndrome
| Autor: | Terezinha C. B. Montelli, Maria Tereza R. Iwasso, Maria Terezinha S. Peraçoli, Norma Gerusa S. Mota |
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| Jazyk: | angličtina |
| Rok vydání: | 1981 |
| Předmět: | |
| Zdroj: | Arquivos de Neuro-Psiquiatria, Vol 39, Iss 1, Pp 1-12 (1981) |
| Druh dokumentu: | article |
| ISSN: | 1678-4227 0004-282X |
| DOI: | 10.1590/S0004-282X1981000100001 |
| Popis: | The immunological status of five children with West syndrome consequent to previous cerebral lesions was investigated. Three children had West syndrome and two were in transition from West to Lennox-Gastaut syndrome. All of them showed cellular immunological deficiencies in the following tests: sensitization to DNCB, intracutaneous reaction to PHA, inhibition of leucocyte migration, blastic transformation of lymphocytes, T and B lymphocytes in peripheric blood and levels of serum immunoglobulins. These immunological deficiencies, of different degrees of severity, were associated to frequent infections in these children. A possible association between the immunological deficiencies and autoimmunity is discussed. |
| Databáze: | Directory of Open Access Journals |
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