Correction of Oxygen Transport and Metabolic Disturbances in Acute Poisoning by Neurotropic Substances

Autor: G. A. Livanov, B. V. Batotsyrenov, A. N. Lodyagin, M. V. Aleksandrov, Kh. V. Batotsyrenova, V. N. Miroshnichenko
Jazyk: English<br />Russian
Rok vydání: 2007
Předmět:
Zdroj: Общая реаниматология, Vol 3, Iss 6, Pp 55-60 (2007)
Druh dokumentu: article
ISSN: 1813-9779
2411-7110
DOI: 10.15360/1813-9779-2007-6-55-60
Popis: Objective: to examine the capacities of pharmacological correction of impairments in oxygen-transporting systems and metabolic processes with perfluorane and cytoflavin in critically ill patients with acute intoxication with neurotropic poisons.Subjects and methods. Metabolic sequels of severe hypoxia, free radical processes, and endogenous intoxications were studied in 62 patients with the severest acute intoxication with neurotropic poisons.Results. The studies have established that hypoxia and metabolic changes lead to the development of endotoxicosis. Intensifying endotoxicosis in turn enhances hypoxic lesion. Thus, the major task of intensive care is to restore oxygen delivery and to diminish metabolic disturbances and endotoxicosis. Ways of correcting hypoxia and metabolic disturbances are considered in the severe forms of acute poisoning.
Databáze: Directory of Open Access Journals