| Autor: |
Wajeeha Khalid, Jamaluddin |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College, Vol 24, Iss 1 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1563-3241 |
| DOI: |
10.58397/ashkmdc.v24i1.27 |
| Popis: |
We describe the case of 66 year old male, known case of COPD and type II diabetes mellitus, with a diagnosis of coeliac disease confirmed by the elevated titers of antigliadin and antiendomysium IgG antibodies together with partial villous atrophy in jejunal histology, complicating to diffuse large B cell lymphoma presented as enterocolic fistula. Laparotomy was performed which included gastrojejun- ostomy to bypass the fistula, ileo-ileal anastomosis to prevent obstruction, and end-transverse colos- tomy. Histology was taken from fistulous tract following laparotomy suspected high-grade non-Hodgkin's lymphoma. Further supplementary reports showed immunoperoxidase studies that the tumor cells are strongly positive for LCA and negative for CD30 and S100. These findings are sug- gestive of high grade non Hodgkins lymphoma which is confirmed by immunohistochemistry results. The biopsy showed high proliferation and soft tissue infiltration by diffuse large B-cell lymphoma which shows extensive apoptosis secondary to a complication of coeliac disease presenting as enterocoloc fistula. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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