Case Report: Multiple autoimmune syndrome (MAS)—An unusual combination

Autor: Elaine Yi Lee Kwong, Manson Chon In Kuok, Winnie Kwai-Yu Chan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Frontiers in Pediatrics, Vol 10 (2022)
Druh dokumentu: article
ISSN: 2296-2360
DOI: 10.3389/fped.2022.1054025
Popis: This is a case report of a Chinese adolescent boy who had multiple autoimmune syndrome (MAS) of a rare combination comprising type 1 diabetes, Hashimoto thyroiditis and childhood-onset systemic lupus erythematosus (SLE). He developed SLE within one year of symptom onset, presenting with necrotising histiocytic lymphadenitis and hepatitis. We highlight the importance for physicians to be aware of the need for continued surveillance for developing new autoimmune diseases in patients with multiple autoimmune diseases. It is also essential to remain vigilant for overlap syndrome as autoimmune diseases commonly share similar subphenotypes and non-specific autoantibodies. Long-term follow-up is warranted to define the final phenotype.
Databáze: Directory of Open Access Journals