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Introduction: Death with a functioning graft (DWFG) is the most frequent cause of loss of kidney transplantation (KT). Objective: To analyze the evolution of the causes of DWFG and the frequency of the types of cancer causing DWFG. Methods: Retrospective study of KT in Andalusia from 1984 to 2018. We analyzed the evolution according to eras (1984–1995; 1996–2007; 2008–2018) and according to post-transplant period (early death: first year post-KT; late death: after first year post-KT). Results: A total of 9905 KT were performed, registering 1861 DWFG. The most frequent causes were cardiovascular disease (25.1%), infections (21.5%) and cancer (19.9%).In early death we did not observe changes, and infections were always the main cause. In late death, cardiovascular death decreased (1984−1995: 35.2%, 1996−2007: 22.6%, 2008−2018: 23.9%), but infections (1984−1995: 12.5%, 1996−2007: 18.3%, 2008−2018: 19.9%) and, above all, cancer-related deaths increased (1984−1995: 21.8%, 1996–2007: 29%, 2008−2018: 26.8%) (P |
