Synthesis, crystal structure, and anti-breast cancer activity of a novel metal-porphyrinic complex [YK(TCPP)(OH)2·(solvents)x]
Autor: | J-C. Liu, J-J. Gu, Y-S. Zhang |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 51, Iss 1 (2017) |
Druh dokumentu: | article |
ISSN: | 1414-431X 1414-431x |
DOI: | 10.1590/1414-431x20176858 |
Popis: | A novel heterometallic metal-porphyrinic framework (MPFs) built from Y and K ions as nods and meso-tetra(4-carboxyphenyl)porphyrin as linkers has been successfully synthesized and characterized. The single crystal X-ray diffraction indicated that this complex 1 exhibited a bilayered architecture of the porphyrins, which is seldom seen in MPFs. In addition, in vitro anticancer activity of complex 1 on three human breast cancer cells (BT474, SKBr-3 and ZR-75-30) was further determined. |
Databáze: | Directory of Open Access Journals |
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