Acute myelogenous leukemia – current recommendations and approaches in molecular-genetic assessment

Autor: Yahya Dinnar, Hachmeriyan Mari, Micheva Ilina, Chervenkov Trifon
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Romanian Journal of Internal Medicine, Vol 60, Iss 2, Pp 103-114 (2022)
Druh dokumentu: article
ISSN: 2501-062X
DOI: 10.2478/rjim-2022-0004
Popis: Acute myelogenous leukemia is a multi-step hematological malignancy, affecting function, growth, proliferation and cell cycle of myeloid precursors. Overall assessment of patients with the disease requires among everything else, a comprehensive investigation of the genetic basis through various methods such as cytogenetic and molecular-genetic ones. This clarification provides diagnostic refinement and carries prognostic and predictive value in respect of essential therapeutic choices.
Databáze: Directory of Open Access Journals