Comparative Analysis of Clinical Severity and Outcomes in Penetrating Versus Blunt Traumatic Brain Injury Propensity Matched Cohorts

Autor: Ali Mansour, Plamena P. Powla, Ronald Alvarado-Dyer, Farima Fakhri, Paramita Das, Peleg Horowitz, Fernando D. Goldenberg, Christos Lazaridis
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Neurotrauma Reports, Vol 5, Iss 1, Pp 348-358 (2024)
Druh dokumentu: article
ISSN: 2689-288X
DOI: 10.1089/NEUR.2024.0009
Popis: Traumatic brain injury (TBI) is a global health challenge; however, penetrating brain injury (PBI) remains under-represented in evidence-based knowledge and research efforts. This study utilized data from the Trauma Quality Improvement Program (TQIP) of the National Trauma Data Bank (NTDB) to investigate outcomes of PBI as compared with clinical-severity-matched non-penetrating or blunt TBI. A total of 1765 patients with PBI were 1:1 propensity score-matched for clinical severity with blunt TBI patients. The intent of PBI was self-inflicted in 34.1% of the cases, and the mechanism was firearm-inflicted in 89.1%. Mortality was found to be significantly more common in PBI than in the severity- matched TBI cohort (33.9% vs. 14.3 %, p?0.001) as was unfavorable outcome. Mortality was mediated by withdrawal of life-sustaining therapies (WOLST) 30% of the time, and WOLST occurred earlier (median 3 days vs. 6 days, p?
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