Reparative effects of paricalcitol and calcitriol in patients with cardiorenal syndrome and chronic allograft nephropathy
| Autor: | A. N. Kharlamov, A. N. Perrish, Ya. L. Gabinskyi, Kh. Ronne, E. Yu. Ivanova |
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| Jazyk: | ruština |
| Rok vydání: | 1970 |
| Předmět: | |
| Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 10, Iss 7, Pp 58-69 (1970) |
| Druh dokumentu: | article |
| ISSN: | 1728-8800 2619-0125 |
| Popis: | Aim. To study the role of vitamin D in the prevention and treatment of cardio-renal syndrome (CRS), chronic allograft nephropathy (CAN), as well as in the renal and cardiac tissue reparation. Material and methods. This randomized, blind, placebo-controlled study included 120 vitamin D-deficient Russian and Dutch patients — recipients of asystolic and cadaver donor kidneys. All participants were divided into 4 groups: 28 subjects received paricalcitol (2-4 μg/d); 28 — calcitriol (1-6 μg/d per os); 26 — diet and multivitamins (daily vitamin D consumption of 1200-1800 IU); and 27 — placebo plus controlled diet. Results. At Day 180, CAN severity reached 1,24 in the paricalcitol group and 1,22 in the calcitriol group, compared to 1,43 and 1,68 in the diet and placebo groups, respectively (p |
| Databáze: | Directory of Open Access Journals |
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