Hypopituitarism as unusual sequelae to central nervous system tuberculosis

Autor:	S Mageshkumar, Devendra V Patil, J A Philo Aarthy, K Madhavan
Jazyk:	angličtina
Rok vydání:	2011
Předmět:	Hyperprolactinemia hypogonadotropism hypopituitarism tuberculomas Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Indian Journal of Endocrinology and Metabolism, Vol 15, Iss 7, Pp 259-262 (2011)
Druh dokumentu:	article
ISSN:	2230-8210 2230-9500
DOI:	10.4103/2230-8210.84881
Popis:	Neurological tuberculosis can very rarely involve the hypophysis cerebri. We report a case of an eighteen year old female who presented with five months duration of generalised apathy, secondary amenorrhea and weight gain. She was on irregular treatment for tuberculosis of the central nervous system for the last five months. Neuroimaging revealed sellar and suprasellar tuberculomas and communicating hydrocephalus requiring emergency decompression. Endocrinological investigation showed hypopituitarism manifesting as pituitary hypothyroidism, hypocortisolism, hypogonadotropic hypogonadism, and hyperprolactinemia. Restarting anti-tuberculosis treatment, hormone replacement therapy, and a ventriculo-peritoneal shunt surgery led to remarkable improvement in the general condition of the patient.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/20ed3483859342f9aaa2a22de3d28485 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF