Autor: |
Lingmin Zheng, Peirong Jiang, Danjie Lin, Xiaodan Chen, Tianjin Zhong, Rufei Zhang, Jing Chen, Yang Song, Yunjing Xue, Lin Lin |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Cancer Imaging, Vol 23, Iss 1, Pp 1-9 (2023) |
Druh dokumentu: |
article |
ISSN: |
1470-7330 |
DOI: |
10.1186/s40644-023-00633-z |
Popis: |
Abstract Background The consistency of meningiomas is critical to determine surgical planning and has a significant impact on surgical outcomes. Our aim was to compare mono-exponential, bi-exponential and stretched exponential MR diffusion-weighted imaging in predicting the consistency of meningiomas before surgery. Methods Forty-seven consecutive patients with pathologically confirmed meningiomas were prospectively enrolled in this study. Two senior neurosurgeons independently evaluated tumour consistency and classified them into soft and hard groups. A volume of interest was placed on the preoperative MR diffusion images to outline the whole tumour area. Histogram parameters (mean, median, 10th percentile, 90th percentile, kurtosis, skewness) were extracted from 6 different diffusion maps including ADC (DWI), D*, D, f (IVIM), alpha and DDC (SEM). Comparisons between two groups were made using Student’s t-Test or Mann-Whitney U test. Parameters with significant differences between the two groups were included for Receiver operating characteristic analysis. The DeLong test was used to compare AUCs. Results DDC, D* and ADC 10th percentile were significantly lower in hard tumours than in soft tumours (P ≤ 0.05). The alpha 90th percentile was significantly higher in hard tumours than in soft tumours (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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