Misoprostol-induced Coronary Vasospasm Complicated by Takotsubo Cardiomyopathy and Cardiac Arrest

Autor: Parminder Kaur, Melvin Santana, Balraj Singh, Anuraag Sah, Raja Pullatt, Fayez Shamoon
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2021)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2021_002674
Popis: Misoprostol is a synthetic E1 prostaglandin commonly used to induce abortion in the United States and elsewhere. There is limited literature on the cardiovascular adverse effects of misoprostol, and, to the best of our knowledge, very few such events have been reported. We describe the case of 52-year-old woman who was given misoprostol for cervical softening before endometrial ablation and experienced a cardiac arrest due to coronary vasospasm. She was successfully resuscitated and echocardiography showed features consistent with Takotsubo cardiomyopathy. Coronary angiography revealed coronary artery spasm which responded to nitroglycerin. Our case adds to the limited literature on this life-threatening adverse event of misoprostol.
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