Clinical Application and Limitations of Myeloma Response Assessment and Diagnosis System (MY-RADS)

Autor: Dong Kyun Kim, Sung-Soo Park, Joon-Yong Jung
Jazyk: English<br />Korean
Rok vydání: 2023
Předmět:
Zdroj: Journal of the Korean Society of Radiology, Vol 84, Iss 1, Pp 51-74 (2023)
Druh dokumentu: article
ISSN: 2951-0805
DOI: 10.3348/jksr.2022.0154
Popis: Multiple myeloma, which is a proliferative disease of plasma cells that originate from a single clone, is the second most common hematologic malignancy following non-Hodgkin lymphoma. In the past, its diagnosis was made based on clinical findings (so-called “CRAB”) and a skeletal survey using radiographs. However, since the implementation of the International Myeloma Working Group’s revised guideline regarding the radiologic diagnosis of multiple myeloma, whole-body (WB) MRI has emerged to play a central role in the early diagnosis of multiple myeloma. Diffusion-weighted imaging and fat quantification using Dixon methods enable treatment response assessment by MRI. In keeping with the trend, a multi-institutional and multidisciplinary consensus for standardized image acquisition and reporting known as the Myeloma Response Assessment and Diagnostic System (MY-RADS) has recently been proposed. This review aims to describe the clinical application of WB-MRI based on MYRADS in multiple myeloma, discuss its limitations, and suggest future directions for improvement.
Databáze: Directory of Open Access Journals