Serum endocan levels, carotid intima-media thickness and microalbuminuria in patients with newly diagnosed hypertension

Autor: Sevil Fisekci Oktar, Ibrahim Guney, Sayeste Akkan Eren, Levent Oktar, Kenan Kosar, Zafer Buyukterzi, Ender Alkan, Zeynep Biyik, Said Sami Erdem
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Clinical and Experimental Hypertension, Vol 41, Iss 8, Pp 787-794 (2019)
Druh dokumentu: article
ISSN: 1064-1963
1525-6006
10641963
DOI: 10.1080/10641963.2019.1652632
Popis: Background: Endocan is a particular protein of endothelial cells. The purpose of this study was to determine the relationship of serum endocan levels with carotid intima-media thickness (cIMT), inflammation, and microalbuminuria in patients with newly-diagnosed hypertension. Materials-Methods: This prospective study included 61 patients with newly-diagnosed hypertension (HT) and 30 controls. Endocan, microalbuminuria and cIMT measurements were taken from all patients. Results: The serum endocan levels, the mean cIMT and microalbuminuria levels of patients with HT were significantly higher than those of the control group (p < .0001, p = .015 and p < .001, respectively). Conclusion: We found that endocan levels were increased in our study. This increase in endocan levels shows a relation with cIMT and microalbuminuria, which are associated with endothelial dysfunction.
Databáze: Directory of Open Access Journals
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