Clinicopathologic characteristics and prognosis for male breast cancer compared to female breast cancer

Autor: Nan Yao, Wenzai Shi, Tong Liu, Sarah Tan Siyin, Weiqi Wang, Ning Duan, Guoshuai Xu, Jun Qu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-04342-0
Popis: Abstract Male breast cancer (MBC) is rare. Due to limited information, MBC has always been understudied. We conducted a retrospective population-based cohort study using data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) program. The clinical and biological features of female breast cancer (FBC) patients were compared with MBC patients. Cox regression models and competing risks analyses were used to identify risk factors associated with cancer-related survival in MBC and FBC groups. Results showed that MBC patients suffered from higher TNM stages, tumor grades, and a higher percentage of hormone receptor-positive tumors, compared with FBC patients (all p 0.05). Tumor location was an independent prognostic factor for both gender groups.
Databáze: Directory of Open Access Journals
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