Autor: |
Jifeng Yu, Bangguo Zhou, Shen Zhang, Haohao Yin, Liping Sun, Yinying Pu, Boyang Zhou, Yikang Sun, Xiaolong Li, Yan Fang, Lifan Wang, Chongke Zhao, Dou Du, Yan Zhang, Huixiong Xu |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-022-35580-z |
Popis: |
Recently, strategies based on the integration of nanotechnology with microbial carriers have been proposed for cancer therapy. Here the authors report the design of an ultrasound-controlled CRISPR/Cas9 gene editing system for IDO1 silencing compounded with the probiotic Lactobacillus rhamnosus GG, showing the induction of anti-tumor immune responses in preclinical cancer models. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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