Dietary flavanones and citrus fruits influence cytokines and thyroid transcription factor-1 in an HDM-induced chronic asthma murine model

Autor: Ensiyeh Seyedrezazadeh, Amin Sabri, Abolfazl Barzegari, Saeed Kolahian, Amir-Ali Shahbazfar, Khalil Ansarin, Mohammadreza Vafa, Ebrahim Sakhinia
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Functional Foods, Vol 26, Iss , Pp 709-718 (2016)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2016.08.033
Popis: The effects of hesperetin plus naringenin, orange juice and grapefruit juice on mRNA expression of TNF-α, TGF-β1 and TTF-1 in a house dust mite (HDM)-induced asthma animal model were investigated. Interventional mice exposed to HDM for 6 weeks received hesperetin plus naringenin, orange plus grapefruit juice, orange juice, grapefruit juice or water during the last 4 weeks, whereas non-asthmatic control mice consumed water. Lung tissue TNF-α and TGF-β1 expressions in supplemented groups were significantly reduced (p
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