| Autor: |
Dibbendhu Khanra, Vikas Mishra, Bhavna Jain, Shishir Soni, Yogesh Bahurupi, Bhanu Duggal, Sudhir Rathore, Santanu Guha, Sharad Agarwal, Puneet Aggarwal, SantoshKumar Sinha, Kumar Himanshu |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Indian Heart Journal, Vol 72, Iss 4, Pp 225-231 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
0019-4832 |
| DOI: |
10.1016/j.ihj.2020.07.013 |
| Popis: |
Aims: Studies comparing the outcome of percutaneous coronary intervention (PCI) along with optimal medical therapy (OMT) versus OMT alone in treatment of chronic total occlusion (CTO) are limited by observational design, variable follow-up period, diverse clinical outcomes, high drop-out and cross-over rates. This study aims to conduct a meta-analysis of published data of observational as well as randomized studies comparing long term outcomes of PCI+OMT versus OMT alone. Methods and results: PubMed, Embase and Cochrane databases were systematically reviewed. 15 studies meeting criteria were included in the meta-analysis. The New-castle Ottawa scale was used to appraise the overall quality of the studies. Random-effects model with inverse variance method was undertaken. Major adverse cardiovascular events (MACE) which comprises of cardiac death, myocardial infarction, stroke, and un-planned revascularization were significantly lower in the PCI+OMT group (RR:0.76; 95% CI:0.61 to 0.95; P= |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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