Structure and mechanism of DNA delivery of a gene transfer agent

Autor: Pavol Bárdy, Tibor Füzik, Dominik Hrebík, Roman Pantůček, J. Thomas Beatty, Pavel Plevka
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Druh dokumentu: article
ISSN: 2041-1723
24552380
DOI: 10.1038/s41467-020-16669-9
Popis: Gene transfer agents (GTAs) are phage-like particles that mediate lateral gene exchange. Here, the authors provide the structure of the GTA of Rhodobacter capsulatus (RcGTA), which resembles a tailed phage, and describe the conformational changes required for DNA ejection.
Databáze: Directory of Open Access Journals