An algorithm to predict the need for invasive mechanical ventilation in hospitalized COVID-19 patients: the experience in Sao Paulo

Autor: Eduardo Atsushi Osawa, Alexandre Toledo Maciel
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Acute and Critical Care, Vol 37, Iss 4, Pp 580-591 (2022)
Druh dokumentu: article
ISSN: 2586-6052
2586-6060
DOI: 10.4266/acc.2022.00283
Popis: Background We aimed to characterize patients hospitalized for coronavirus disease 2019 (COVID-19) and identify predictors of invasive mechanical ventilation (IMV). Methods We performed a retrospective cohort study in patients with COVID-19 admitted to a private network in Sao Paulo, Brazil from March to October 2020. Patients were compared in three subgroups: non-intensive care unit (ICU) admission (group A), ICU admission without receiving IMV (group B) and IMV requirement (group C). We developed logistic regression algorithm to identify predictors of IMV. Results We analyzed 1,650 patients, the median age was 53 years (42–65) and 986 patients (59.8%) were male. The median duration from symptom onset to hospital admission was 7 days (5–9) and the main comorbidities were hypertension (42.4%), diabetes (24.2%) and obesity (15.8%). We found differences among subgroups in laboratory values obtained at hospital admission. The predictors of IMV (odds ratio and 95% confidence interval [CI]) were male (1.81 [1.11–2.94], P=0.018), age (1.03 [1.02–1.05], P
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