Changing epidemiology of COVID-19: potential future impact on vaccines and vaccination strategies
| Autor: | Timo Ulrichs, Morgane Rolland, Jianhong Wu, Marta C Nunes, Clotilde El Guerche-Séblain, Ayman Chit |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Expert Review of Vaccines, Vol 23, Iss 1, Pp 510-522 (2024) |
| Druh dokumentu: | article |
| ISSN: | 14760584 1744-8395 1476-0584 |
| DOI: | 10.1080/14760584.2024.2346589 |
| Popis: | Introduction COVID-19 was an unprecedented challenge worldwide; however, disease epidemiology has evolved, and COVID-19 no longer constitutes a public health emergency of international concern. Nonetheless, COVID-19 remains a global threat and uncertainties remain, including definition of the end of the pandemic and transition to endemicity, and understanding true rates of SARS-CoV-2 infection/transmission.Areas covered Six international experts convened (April 2023) to interpret changing COVID-19 epidemiology and public health challenges. We report the panel’s recommendations and knowledge gaps in COVID-19 epidemiology, SARS-CoV-2 evolution, and future vaccination strategies, informed by peer-reviewed publications, surveillance data, health authority assessments, and clinical experience.Expert opinion High population SARS-CoV-2 immunity indicates the likely end to the pandemic’s acute phase. Continued emergence of variants/sublineages that can evade the vaccine-induced antibody response are likely, but widespread immunity reduces the risk of disease severity. Continued surveillance is required to capture transition to endemicity, seasonality, and emergence of novel variants/sublineages, to inform future vaccination strategies. COVID-19 vaccination should be integrated into routine vaccination programs throughout life. Co-circulation with other respiratory viruses should be monitored to avoid a combined peak, which could overrun healthcare systems. Effective, combined vaccines and improved education may help overcome vaccine hesitancy/booster fatigue and increase vaccination uptake. |
| Databáze: | Directory of Open Access Journals |
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