Impact of data source choice on multimorbidity measurement: a comparison study of 2.3 million individuals in the Welsh National Health Service

Autor: Clare MacRae, Daniel Morales, Stewart W. Mercer, Nazir Lone, Andrew Lawson, Emily Jefferson, David McAllister, Marjan van den Akker, Alan Marshall, Sohan Seth, Anna Rawlings, Jane Lyons, Ronan A. Lyons, Amy Mizen, Eleojo Abubakar, Chris Dibben, Bruce Guthrie
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Druh dokumentu: article
ISSN: 1741-7015
DOI: 10.1186/s12916-023-02970-z
Popis: Abstract Background Measurement of multimorbidity in research is variable, including the choice of the data source used to ascertain conditions. We compared the estimated prevalence of multimorbidity and associations with mortality using different data sources. Methods A cross-sectional study of SAIL Databank data including 2,340,027 individuals of all ages living in Wales on 01 January 2019. Comparison of prevalence of multimorbidity and constituent 47 conditions using data from primary care (PC), hospital inpatient (HI), and linked PC-HI data sources and examination of associations between condition count and 12-month mortality. Results Using linked PC-HI compared with only HI data, multimorbidity was more prevalent (32.2% versus 16.5%), and the population of people identified as having multimorbidity was younger (mean age 62.5 versus 66.8 years) and included more women (54.2% versus 52.6%). Individuals with multimorbidity in both PC and HI data had stronger associations with mortality than those with multimorbidity only in HI data (adjusted odds ratio 8.34 [95% CI 8.02-8.68] versus 6.95 (95%CI 6.79-7.12] in people with ≥ 4 conditions). The prevalence of conditions identified using only PC versus only HI data was significantly higher for 37/47 and significantly lower for 10/47: the highest PC/HI ratio was for depression (14.2 [95% CI 14.1–14.4]) and the lowest for aneurysm (0.51 [95% CI 0.5–0.5]). Agreement in ascertainment of conditions between the two data sources varied considerably, being slight for five (kappa
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje