Retinal nerve fiber layer sector-specific compromise in relapsing and remitting multiple sclerosis

Autor: Anette S. Loughran-Fjeldstad, Noel G. Carlson, Cassandra D. Husebye, Lawrence J. Cook, John W. Rose
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: eNeurologicalSci, Vol 1, Iss 2, Pp 30-37 (2015)
Druh dokumentu: article
ISSN: 2405-6502
DOI: 10.1016/j.ensci.2015.09.004
Popis: Objective: To evaluate quadrant and sector retinal nerve fiber layer (RNFL) thickness and total macular volume (TMV) in relapsing–remitting multiple sclerosis (RR-MS) patients. Methods: Optical coherence tomography measures of RNFL and TMV were studied in 321 eyes without prior optic neuritis (ON) (MS unaffected), 151 eyes with prior ON (MS affected), and 148 healthy control eyes. Results: Mean RNFL thickness was significantly lower in the MS affected and MS unaffected groups relative to the control group (p
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