A Straightforward and High-Yielding Synthesis of 1,2,4-Oxadiazoles from Chiral N-Protected α-Amino Acids and Amidoximes in Acetone-Water: An Eco-Friendly Approach

Autor: André C. Sauer, Lucas Wolf, Natália Quoos, Mariele B. Rodrigues, Antônio L. Braga, Oscar E. D. Rodrigues, Luciano Dornelles
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Chemistry, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 2090-9063
2090-9071
DOI: 10.1155/2019/8589325
Popis: A straightforward and high-yielding methodology for the synthesis of a high structural diversity of 1,2,4-oxadiazoles from different chiral N-protected α-amino acids and amidoximes under microwave (MW) irradiation is described herein. This greener approach gives the desired products using acetone/water as solvent in very short reaction times.
Databáze: Directory of Open Access Journals
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