ECMO support as a bridge to lung transplantation is an independent risk factor for bronchial anastomotic dehiscence

Autor: Enora Atchade, Mélissa Ren, Sylvain Jean-Baptiste, Alexy Tran Dinh, Sébastien Tanaka, Parvine Tashk, Brice Lortat-Jacob, Maksud Assadi, Gaelle Weisenburger, Hervé Mal, Jean Nicolas Sénémaud, Yves Castier, Christian de Tymowski, Philippe Montravers
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 1471-2466
DOI: 10.1186/s12890-022-02280-9
Popis: Abstract Background Airway complications are frequent after lung transplantation (LT), as they affect up to 23% of recipients. The implication of perioperative extracorporeal membrane oxygenation (ECMO) support and haemodynamic instability has never been specifically assessed. The first aim of this study was to explore the impact of perioperative ECMO support on bronchial anastomotic dehiscence (BAD) at Day 90 after LT. Methods This prospective observational monocentric study analysed BAD in all consecutive patients who underwent LT in the Bichat Claude Bernard Hospital, Paris, France, between January 2016 and May 2019. BAD visible on bronchial endoscopy and/or tomodensitometry was recorded. A univariate analysis was performed (Fisher’s exacts and Mann–Whitney tests), followed by a multivariate analysis to assess independent risk factors for BAD during the first 90 days after LT (p
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