Ocotea nutans (Nees) Mez (Lauraceae): chemical composition, antioxidant capacity and biological properties of essential oil

Autor: Fernando Cesar Martins Betim, Camila Freitas de Oliveira, Angela Maria de Souza, Ellis Marina Szabo, Sandra Maria Warumby Zanin, Obdulio Gomes Miguel, Marilis Dallarmi Miguel, Josiane de Fátima Gaspari Dias
Jazyk: angličtina
Předmět:
Zdroj: Brazilian Journal of Pharmaceutical Sciences, Vol 55
Druh dokumentu: article
ISSN: 2175-9790
DOI: 10.1590/s2175-97902019000118284
Popis: The present study was undertaken to assess the potential uses of the essential oil obtained from Ocotea nutans (Nees) Mez. The hydrodistilled essential oil from O. nutans leaves was analyzed by gas chromatography-mass spectrometry. Fifty-eight compounds representing 87,29% of the total leaf essential oil components were identified, of which biciclogermacrene(11.41%), germacrene-D (4.89%), bisabolol-11-ol(3.73%) and spathulenol (3.71%) were the major compounds. The essential oil from O. nutans were tested for antibacterial activity using the minimum inhibitory concentracion (MIC) method, Artemia salina method, larvicidal activity in Aedes aegypti, and antioxidant capacity.The antioxidant activity measured by the phosphomolybdenum complex and Prussian blue method had positive results. The minimum inhibitory concentration for the microorganisms tested allowed moderate inhibitionfor Enterococcus faecalis(MIC=500 µg/mL). Artemia salina were toxic to the organisms in the study (LC50= 71,70 μg /mL). The essential oil showed remarkable larvicidal activity potencial (LC50= 250 µg/mL). The present results showed thatO. nutans essential oil has potential biological uses.
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