Virulence attenuation and phenotypic variation of Paracoccidioides brasiliensis isolates obtained from armadillos and patients

Autor:	SAG Macoris, MF Sugizaki, MTS Peraçoli, SMG Bosco, F Hebeler-Barbosa, LB Simões, RC Theodoro, LA Trinca, E Bagagli
Jazyk:	angličtina
Rok vydání:	2006
Předmět:	Paracoccidioides brasiliensis virulence hamster Dasypus novemcinctus Microbiology QR1-502 Infectious and parasitic diseases RC109-216
Zdroj:	Memorias do Instituto Oswaldo Cruz, Vol 101, Iss 3, Pp 331-334 (2006)
Druh dokumentu:	article
ISSN:	0074-0276 1678-8060
DOI:	10.1590/S0074-02762006000300019
Popis:	Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis, the most important systemic mycosis in Latin America. The virulence profiles of five isolates of P. brasiliensis were studied in two different moments and correlated with some colonial phenotypic aspects. We observed a significant decrease in the virulence and an intense phenotypic variation in the mycelial colony. The recognition of all ranges of phenotypic and virulence variation of P. brasiliensis, as well as its physiological and genetic basis, will be important for a better comprehension of its pathogenic and epidemiological features.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1ffcd3f4028543a9ba0a2dea0b21e3a1 Zobrazit plný text záznamu View record in DOAJ