Plasmonic Sensing of Glucose Based on Gold–Silver Core–Shell Nanoparticles

Autor: Junjie Wang, Xiaoping Yue, Yulong Zhang, Chengcheng Zhu, Xing Kang, Hai-Dong Yu, Gang Lu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Chemosensors, Vol 10, Iss 10, p 404 (2022)
Druh dokumentu: article
ISSN: 2227-9040
DOI: 10.3390/chemosensors10100404
Popis: Developing a simple and convenient approach for glucose sensing is crucially important in disease diagnosis and health monitoring. In this work, a glucose sensor based on plasmonic nanostructures was developed using gold–silver core–shell nanoparticles as the sensing platform. Based on the oxidative etching of the silver shell, the concentration of hydrogen peroxide and glucose could be determined quantitatively via the spectral change. This spectral change could also be observed with the naked eye or with a phone camera, realizing colorimetric sensing. To demonstrate this, glucose solutions at different concentrations were quantitatively detected in a wide concentration range of 0–1.0 mM using this colorimetric sensor. Importantly, shell thickness could significantly affect the sensitivity of our colorimetric sensor. This work provides a deeper understanding of the plasmonic sensing of glucose, which will help to realize its real applications. Based on this strategy, the non-invasive sensing of metabolites may be realized for disease diagnosis and health monitoring.
Databáze: Directory of Open Access Journals