Coinfection with Mycoplasma Pneumoniae and Chlamydia Pneumoniae in ruptured plaques associated with acute myocardial infarction
| Autor: | Maria de Lourdes Higuchi, Marcia Martins Reis, Nádia Vieira Sambiase, Suely Aparecida Pinheiro Palomino, Jussara Bianchi Castelli, Paulo Sampaio Gutierrez, Vera Demarchi Aiello, José Antonio Franchini Ramires |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Arquivos Brasileiros de Cardiologia, Vol 81, Iss 1, Pp 12-22 (2003) |
| Druh dokumentu: | article |
| ISSN: | 0066-782X 1678-4170 |
| DOI: | 10.1590/S0066-782X2003000900001 |
| Popis: | OBJECTIVE: To study atheromas, Mycoplasma pneumoniae (M. pneumoniae), and Chlamydia pneumoniae (C. pneumoniae). METHODS: C. pneumoniae was studied with immunohistochemistry and M. pneumoniae with in situ hybridization (ISH), in segments of coronary arteries (SCA) as follows: group A - thrombosed ruptured plaques (TRP) of 23 patients who died due to acute myocardial infarction (AMI); group B - 23 nonruptured plaques (NRP) of group A patients; group C - NRP of 11 coronary patients who did not die due to AMI; and group D - 11 SCA from patients with dilated cardiomyopathy or Chagas' disease without atherosclerosis. RESULTS: The mean number of C. pneumoniae+ cells/400x in groups A, B, C, and D was, respectively, 3.3±3.6; 1.0±1.3; 1.2±2.4; and 0.4±0.3; and the percentage of M. pneumoniae area was, respectively, 3.9±3.5; 1.5± 1.6; 0.9±0.9; and 0.4±0.2. More M. pneumoniae and C. pneumoniae were found in of group A than in group B (P |
| Databáze: | Directory of Open Access Journals |
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