Investigate the protective effect of Marjoram and Vitamin C on the tissue structure of the testis after rotation and re-rotation in Rats

Autor: Mohammad Behbahani, Elham Moghtadaei-Khorasgani, Mehdi Farid
Jazyk: perština
Rok vydání: 2023
Předmět:
Zdroj: مجله علوم پزشکی فیض (پیوسته), Vol 27, Iss 2, Pp 131-143 (2023)
Druh dokumentu: article
ISSN: 3060-5806
3060-5814
Popis: Background: Testicular torsion is caused by the rotation of the spermatic cord and an emergency case, so surgery is necessary to correct the torsion and treat acute ischemia. One of the treatment methods to reduce complications is the use of herbal compounds. This study aimed to investigate the effects of marjoram and Vitamin C on testicular torsion in order to reduce its complications. Materials and Methods: For this purpose, 30 adult male Wistar rats were used, which were randomly divided into 5 groups of 6 and were treated for 21 days. The control group was given distilled water orally. The positive control group had rotation/recirculation induction without receiving extract and vitamin C. The other groups received induction of rotation/re-rotation with one of the cases in this way: The third group: injection of marjoram extract (250 mg/kg), the fourth group: injection of vitamin C (20 mg/kg), the fifth group: injection of vitamin C and marjoram. At the end, histopathological parameters, sperm parameters and oxidative stress factors were evaluated with ANOVA test. Results: The average percentage of progressive movements, normal shapes and the number of sperms in the groups treated with vitamin C and marjoram extract significantly (P
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