Advances in Pseudoprogression of Immune Checkpoint Inhibitors in Non-small Cell Lung Cancer

Autor:	Yajun TONG, Yong LONG, Fan ZHANG, Junfeng LI
Jazyk:	čínština
Rok vydání:	2024
Předmět:	lung neoplasms immune checkpoint inhibitors pseudoprogression immunotherapy Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Chinese Journal of Lung Cancer, Vol 27, Iss 4, Pp 306-320 (2024)
Druh dokumentu:	article
ISSN:	1009-3419 1999-6187
DOI:	10.3779/j.issn.1009-3419.2024.101.10
Popis:	The advent of immune checkpoint inhibitors (ICIs) has greatly improved the prognosis of advanced lung cancer patients, but can lead to pseudoprogression (PsP), which complicates clinical evaluation and management. PsP is manifested as temporary enlargement of the tumour or the appearance of new lesions, etc., and improvement in imaging occurs with continued treatment, mostly without worsening of clinical symptoms. Currently, there are still difficulties in the early diagnosis of PsP, and its occurrence mechanism is not yet clear, lacking good predictive factors and related biomarkers. This article reviews the current research status of PsP of ICIs in non-small cell lung cancer in order to provide helpful clinical strategies for oncologists using these drugs.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d1fb7bf144eb42d4ac396dde70fcd7a2 Zobrazit plný text záznamu View record in DOAJ