Non-specific biological markers as a screening test for diagnostic of extrapulmonary tuberculosis

Autor:	Stevanovic G., Pelemis M., Pelemis S., Pavlovic M.
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Tuberculosis adenosine deaminase immunoglobulin G fever of unknown origin laboratory tests Biology (General) QH301-705.5
Zdroj:	Archives of Biological Sciences, Vol 64, Iss 2, Pp 489-495 (2012)
Druh dokumentu:	article
ISSN:	0354-4664 1821-4339
DOI:	10.2298/ABS1202489S
Popis:	Serum concentrations of adenosine deaminase were determined in 223 febrile patients. In 62, we discovered extrapulmonary tuberculosis. Serum levels of immunoglobulin G were monitored in 287 febrile patients, and 68 had extra-pulmonary tuberculosis. Serum concentrations of adenosine deaminase were significantly higher in patients with tuberculosis compared to other patients with fever of unknown origin. Serum concentrations declined during antituberculosis therapy. A correlation with the localization of infection was not found. Levels of immunoglobulin G were higher in patients with tuberculosis. Both tests had high sensitivity and specificity and could therefore be used for screening extrapulmonary tuberculosis; however, they can only be interpreted adequately following a full clinical investigation.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1fb5d6b9d78c44c6902352f53deab80b Zobrazit plný text záznamu View record in DOAJ