Correlation between fear of disease progression and quality-of-life in non-dialysis patients with chronic kidney disease in stages 3-5

Autor: Yun-fei Wang, Yu-yu Zhu, De-guang. Wang
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Linchuang shenzangbing zazhi, Vol 24, Iss 8, Pp 643-650 (2024)
Druh dokumentu: article
ISSN: 1671-2390
DOI: 10.3969/j.issn.1671-2390.2024.08.005
Popis: Objective To evaluate the influencing factors of fear of disease progression and examine its impact on quality-of-life in non-dialysis patients with chronic kidney disease (CKD) in stages 3-5. Methods From June 2022 to May 2023, 130 non-dialysis CKD patients in stages 3-5 were examined by Fear of Progression Questionnaire-Short Form (FoP-Q-SF) and Mos 36-item short-form health survey (SF-36). General demographics and clinical related parameters were recorded. Degree of FoP, its influencing factors and correlation with quality-of-life were explored. Results Average score of FoP-Q-SF was (32.84 ± 6.13) and 43.84% of them fulfilled the dysfunctional fear of progression criterion (score≥34). Multiple stepwise linear regression analysis indicated that age (t = −2.024), education level (t = −2.690), emotional state (t = 6.808), disease stage (t = 2.134) and abnormal calcium & phosphorus metabolism (t = −2.099) were the influencing factors for fear of disease progression (P<0.05). Quality-of-life scores of CKD patients were lower than those of Chinese normative scores and quality-of-life was lower. In patients with FoP-Q-SF score equal or greater than 34 points, scores of each dimension of SF-36 scale were significantly lower than those with FoP-Q-SF score <34 points (P<0.05). A significant negative correlation existed between FoP and quality-of-life in non-dialysis CKD patients in stages 3-5. Conclusion In patients with non-dialysis CKD, fear of disease progression seriously affects their quality-of-life. It is correlated with age, education level, emotional state, disease stage and abnormal calcium & phosphorus metabolism. Physicians should devote greater efforts to health education and social supports.
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