| Autor: |
Ahmed Walid A. Morad, Mohamed A. Elhadi Farag |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Middle East Fertility Society Journal, Vol 20, Iss 3, Pp 182-187 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1110-5690 |
| DOI: |
10.1016/j.mefs.2014.08.004 |
| Popis: |
Objectives: To investigate the endometrial effects of letrozole in PCOS women with poor endometrial response (endometrium thickness ⩽7 mm) to clomiphene citrate (CC) despite adequate ovulation, using the ultrasonographic markers of endometrial receptivity. Study design: Ambidirectional cohort study. Patients and methods: Sixty women with anovulatory PCOS having endometrial thickness less than 7 mm despite adequate ovulation with CC underwent ovulation induction with Letrozole (5 mg/day from cycle day 3 to 7) for one treatment cycle. Main outcome measures: Comparison of the endometrial thickness (ET) and pattern, uterine artery and spiral artery, resistance index (RI) and pulsatility index (PI) between the current letrozole and previous CC stimulated cycles. Results: In the current letrozole cycle compared with the previous CC cycles, there were significantly greater midcycle endometrial thickness (8.97 ± 1.32 vs. 5.7 ± 1.2, respectively; P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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