Screening of anti-oxidant and anti-bacterial metabolites from brown algae Turbinaria ornata for inhibits the multi-drug resistant P. aeruginosa

Autor: Naiyf S. Alharbi, Sami A. Alyahya, Govindan Ramachandran, Chenthis Kanisha Chelliah, Shine Kadaikunnan, Jamal M. Khaled, Khalid F. Alanzi, Govindan Rajivgandhi, Natesan Manoharan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of King Saud University: Science, Vol 32, Iss 8, Pp 3447-3453 (2020)
Druh dokumentu: article
ISSN: 1018-3647
DOI: 10.1016/j.jksus.2020.10.005
Popis: In this study, the anti-oxidant and anti-bacterial activity of marine brown algae Turbinaria ornata (T. ornate) extract was purified by soxhlet apparatus method. The invitro studies of total anti-oxidant activity and DPPH hydroxyl scavenging activity assays were suggested that the T. ornata extract has more anti-oxidant activity. Agar well diffusion and minimum inhibition concentration results were exhibited excellent inhibition effect of T. ornata extract against P. aeruginosa at 300 µg/mL concentration. The time-dependent bacterial inhibition assay was also confirmed the 300 µg/mL concentration at 24 h. Further, the increased death cells and extracellular shape alteration results were observed by confocal laser scanning electron microscope and scanning electron microscope. Therefore, our result was suggested that the T. ornata extract as a promising anti-bacterial agent for multi-drug resistant P. aeruginosa.
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