Mielograma de ratas com disfunção tireoidiana
| Autor: | R.D Castro, J.F Silva, N.M Ocarino, J.N Boeloni, P.P Nunes, G.R Silva, M.M Melo, P.R.O Paes, R Serakides |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia, Vol 63, Iss 5, Pp 1246-1250 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1678-4162 0102-0935 |
| DOI: | 10.1590/S0102-09352011000500030 |
| Popis: | The cells of the myelo id, lymphoid , and erythroid lineage s of the bone marrow were quantified in rats with hypo and hyperthyroidism. Fifteen Wistar rats were divided into three groups: hypothyroid (n=5), hyperthyroid (n=5) , and control (n=5). Three months after the onset of the treatment s, euthanasia was performed . Bone marrow was aspirated from femurs of each animal to perform smear s that were stained with Quick Panoptic. T he percentage s of rubroblast, prorubrocyte, metarubrocyte, myeloblast, promyelocytes, metamyelocytes, myel ocytes, segmented, eosinophils, basophils, lymphocytes, plasma cells and monocytes in were determined a total of 500 cells. The bone marrow of animals with hypothyroidism had hypoplasia. The myeloid:erythroid ratio was higher in animals with thyroid dysfun ction. In hypo and hyperthyroidism, there was a significant reduction of the percentage of rubrocyte, metarubrocyte , and lymphocytes and increase of myelocytes and segmented cells. In hypothyroidism, there was a significant increase in the percentage of me tamyelocytes. It is c oncluded that both hypo and hyperfunction of thyroid increase the myeloid:erythroid ratio by increasing the number of cells of the myeloid lineage and reducing the cells of the erythroid lineage. |
| Databáze: | Directory of Open Access Journals |
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