CyEnGNet—App: A new Cytoscape app for the reconstruction of large co-expression networks using an ensemble approach

Autor: Dulcenombre M. Saz-Navarro, Aurelio López-Fernández, Francisco A. Gómez-Vela, Domingo S. Rodriguez-Baena
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: SoftwareX, Vol 25, Iss , Pp 101634- (2024)
Druh dokumentu: article
ISSN: 2352-7110
DOI: 10.1016/j.softx.2024.101634
Popis: The construction of gene co-expression networks is an essential tool in Bioinformatics for discovering useful biological knowledge. There are a multitude of methodologies related to the construction of this type of network, and one of them is EnGNet, which carries out a joint and greedy approach to the reconstruction of large gene coexpression networks. This work introduces CyEnGNet-App, a Cytoscape application designed to integrate and leverage the EnGNet algorithm. The application allows dynamic interaction and visualisation of gene networks and integration with other Cytoscape applications. CyEnGNet-App is a valuable addition to the field of Bioinformatics, improving the reconstruction of genetic networks and providing a more accessible and efficient user experience in Cytoscape.
Databáze: Directory of Open Access Journals