Autor: |
Lourdes Guerrios‐Rivera, Jessica L. Janes, Amanda M. De Hoedt, Zachary Klaassen, Martha K. Terris, Matthew R. Cooperberg, Christopher L. Amling, Christopher J. Kane, William J. Aronson, Jay H. Fowke, Stephen J. Freedland |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Cancer Medicine, Vol 13, Iss 4, Pp n/a-n/a (2024) |
Druh dokumentu: |
article |
ISSN: |
2045-7634 |
DOI: |
10.1002/cam4.7012 |
Popis: |
Abstract Background We previously reported that outcomes after radical prostatectomy (RP) were similar among non‐Hispanic Black, non‐Hispanic White, and Hispanic White Veterans Affairs (VA) patients. However, prostate cancer (PC) mortality in Puerto Rican Hispanics (PRH) may be higher than in other Hispanic groups. Data focused on PRH patients is sparse; thus, we tested the association between PR ethnicity and outcomes after RP. Methods Analysis included men in SEARCH cohort who underwent RP (1988–2020, n = 8311). PRH patients (n = 642) were treated at the PR VA, and outcomes were compared to patients treated in the Continental US regardless of race. Logistic regression was used to test the associations between PRH and PC aggressiveness, adjusting for demographic and clinicopathological features. Multivariable Cox models were used to investigate PRH versus Continental differences in biochemical recurrence (BCR), metastases, castration‐resistant PC (CRPC), and PC‐specific mortality (PCSM). Results Compared to Continental patients, PRH patients had lower adjusted odds of pathological grade group ≥2 (p |
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