Tuberculous gummas: Epidemiological, clinical, bacteriological, immunological, and therapeutic features
| Autor: | Achraf Machan, Tarik Hanafi, Naoufal Hjira, Mohammed Boui |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | International Journal of Mycobacteriology, Vol 7, Iss 3, Pp 203-211 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2212-5531 2212-554X |
| DOI: | 10.4103/ijmy.ijmy_83_18 |
| Popis: | Tuberculous gummas are an unusual form of tuberculosis (TB) accounting for 1%–2% of all cutaneous TB cases. The aim of this article was to describe the epidemiological, clinical, bacteriological, immunological, and therapeutic features of this form upon a case report and a literature review. Forty-eight case reports were identified through a PubMed and Google Scholar search using the following keywords: “tuberculous gumma” and “metastatic tuberculous abscesse.” Tuberculous gumma can occur at any age. Immunodepression is not a sine qua non condition to the development of the disease. Limbs are the most frequent site for gummas. Tuberculous gummas are associated to another location in only 73% of cases. The most frequent associated locations are lung, nodes, and musculoskeletal apparatus. Mantoux test is negative in 38% of cases. Skin stain is positive in 45% of cases and culture in 85% of cases. Giant epithelioid cell granuloma is present in 82.4% of cases. There is no universally accepted chemotherapy regimen for metastatic tuberculous abscesses. The classic 2RHZE/4RH is highly effective. |
| Databáze: | Directory of Open Access Journals |
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