Higher incidence of acute symptomatic seizures in probable antibody-negative pediatric autoimmune encephalitis than in major antibody-positive autoimmune encephalitis

Autor:	Naoki Yamada, Takeshi Inoue, Ichiro Kuki, Naohiro Yamamoto, Masataka Fukuoka, Megumi Nukui, Hideo Okuno, Junichi Ishikawa, Kiyoko Amo, Masao Togawa, Hiroshi Sakuma, Shin Okazaki
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	pediatric autoimmune encephalitis antibody-negative seizure epilepsy Neurology. Diseases of the nervous system RC346-429
Zdroj:	Frontiers in Neurology, Vol 15 (2024)
Druh dokumentu:	article
ISSN:	1664-2295 13241419
DOI:	10.3389/fneur.2024.1418083
Popis:	PurposeTo delineate the characteristics of probable antibody-negative pediatric autoimmune encephalitis (probable Ab-negative AE), we compared the clinical features of probable Ab-negative AE to those of major antibody-positive AE.MethodsWe retrospectively reviewed the clinical features of 18 patients with probable Ab-negative AE, 13 with anti-N-methyl-D-aspartate receptor encephalitis (NMDARE), and 13 with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). Clinical characteristics, neuroimaging findings, treatments, and outcomes were analyzed.ResultsThe age of onset and length of hospital stay were significantly higher in the NMDARE group than in the other groups (p = 0.02 and p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1f75f999a132414192fffe11ad3c3ab1 Zobrazit plný text záznamu View record in DOAJ