A multicenter retrospective study assessing progression of biliary sludge in dogs using ultrasonography

Autor: Thomas Butler, Nick Bexfield, Cecile Dor, Nicoletta Fantaconi, Iris Heinsoo, Darren Kelly, Andrew Kent, Matthew Pack, Susanna J. Spence, Patricia M. Ward, Penny Watson, Katie E. McCallum
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Veterinary Internal Medicine, Vol 36, Iss 3, Pp 976-985 (2022)
Druh dokumentu: article
ISSN: 1939-1676
0891-6640
79108083
DOI: 10.1111/jvim.16423
Popis: Abstract Background Biliary sludge (BS) frequently is identified on ultrasonographic examination and is described as incidental. It is hypothesized that biliary stasis and hypersecretion play a role in both BS and gallbladder mucocele (GBM) formation. Recent studies have documented similarities in composition of BS and GBM, and there are several examples of progression from BS to GBM in the veterinary literature. Objectives To assess the relationship between the presence of BS and later development of GBM in dogs, over time periods >12 months. Animals A total of 154 dogs with BS and ultrasonographic follow‐up >12 months. Methods Medical records were retrospectively collected from 9 UK‐based referral centers for all available time points. A semiobjective scoring system was used to track volume of BS within the gall bladder (GB) over time. Results Twenty dogs developed GBM during the study period. Shetland Sheepdogs (odds ratio [OR], 40.99; 95% confidence interval [CI], 3.61‐465.95; P = .003) and Border Terriers (OR, 11.66; 95% CI, 3.28‐46.63; P
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